FITC标记的电压门控钾通道蛋白KVβ.2抗体
产品名称： FITC标记的电压门控钾通道蛋白KVβ.2抗体
英文名称： Anti-Kv beta 2/FITC
产品编号： HZ-12182R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Kv beta 2/FITC Conjugated antibody
FITC标记的电压门控钾通道蛋白KVβ.2抗体
| 英文名称 | Anti-Kv beta 2/FITC |
| 中文名称 | FITC标记的电压门控钾通道蛋白KVβ.2抗体 |
| 别 名 | AKR6A5; HKv beta 2; HKvbeta 2; HKvbeta2.1; HKvbeta2.2; K(+) channel subunit beta 2; K+ channel beta 2 subunit; KCNA2B; KCNAB 2; KCNAB2; KCNK2; Kv Beta 2; Kvbeta2; MGC117289; Potassium channel shaker chain beta 2; Potassium voltage gated channel shaker related subfamily; Potassium voltage gated channel shaker related subfamily beta member 2; Voltage gated potassium channel beta 2 subunit; Voltage gated potassium channel subunit beta 2; KCAB2_HUMAN; Voltage-gated potassium channel subunit beta-2; AltName: Full=K(+) channel subunit beta-2; AltName: Full=Kv-beta-2; hKvbeta2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 神经生物学 通道蛋白 细胞膜受体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Zebrafish, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 41kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KCNA2B/Kv beta 2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2010] Function: Voltage gated potassium (Kv) channels represent the most complex class of voltage gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence related potassium channel genes: shaker, shaw, shab, and shal, have been identified in Drosophila, and each has been shown to have human homolog(s). This protein belongs to the potassium channel, voltage gated, shaker related subfamily and is one of the beta subunits, which are auxiliary proteins associating with functional Kv alpha subunits. This member alters functional properties of the KCNA4 gene product. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms. Subunit: Forms heteromultimeric complex with alpha subunits. Forms a ternary complex with SQSTM1 and PRKCZ (By similarity). Subcellular Location: Cytoplasmic Post-translational modifications: Phosphorylated by PRKCZ; may be regulated by incorporation in a complex composed of PRKCZ and SQSTM1 (By similarity). Similarity: Belongs to the shaker potassium channel beta subunit family. Database links: Entrez Gene: 8514 Human Entrez Gene: 16498 Mouse Entrez Gene: 29738 Rat Omim: 601142 Human SwissProt: Q13303 Human SwissProt: P62482 Mouse SwissProt: Q3UPV6 Mouse SwissProt: q64284 Mouse SwissProt: P62483 Rat Unigene: 440497 Human Unigene: 10757 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
电压门控钾（Kv）通道从功能和结构的角度代表了最复杂的电压门控离子通道。它们的多种功能包括调节神经递质释放、心率、胰岛素分泌、神经元兴奋性、上皮电解质转运、平滑肌收缩和细胞体积。在果蝇中已经鉴定出四个序列相关的钾通道基因——shaker、shaw、shab和shal，并且每个基因都具有人类同源性。该基因编码钾通道的成员，电压门控，振荡器相关子家族。该成员是β亚基之一，它是与功能KVα亚基相关的辅助蛋白。该成员改变KCNA4基因产物的功能性质。该基因的选择性剪接导致编码不同亚型的多个转录变体。[ RefSeq提供，DEC 2010 ]