FITC标记小鼠抗人CD14单克隆抗体-抗体-抗体-生物在线
上海沪震实业有限公司
FITC标记小鼠抗人CD14单克隆抗体

FITC标记小鼠抗人CD14单克隆抗体

商家询价

产品名称: FITC标记小鼠抗人CD14单克隆抗体

英文名称: human CD14-FITC

产品编号: hzm-30074M-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: Flow-Cyt=20ul/Test

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 Mouse Anti-human CD14-FITC antibody

 

产品编号 hzm-30074M-FITC
英文名称 human CD14-FITC
中文名称 FITC标记小鼠抗人CD14单克隆抗体
别    名 CD14 antigen; CD14 molecule; Lipopolysaccharide receptor; LPSR; Monocyte Differentiation Antigen 14; Monocyte differentiation antigen CD14; Myeloid cell specific leucine rich glycoprotein; CD14_MOUSE; Myeloid cell-specific leucine-rich glycoprotein.  FITC anti-human CD14
   
研究领域 细胞生物  免疫学  干细胞  细胞表面分子  细胞类型标志物  淋巴细胞  
抗体来源 Mouse
克隆类型 Monoclonal
交叉反应 Human, 
产品应用 Flow-Cyt=20ul/Test (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 35/40kDa
细胞定位 细胞膜 
性    状 Liquid
免 疫 原
亚    型 IgG
纯化方法 affinity purified by Protein G
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Mar 2010]

Function:
Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.

Subunit:
Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, MD-2 and TLR4.

Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor.

Similarity:
Contains 11 LRR (leucine-rich) repeats.

SWISS:
P08571

Gene ID:
929

Database links:

Entrez Gene: 929 Human

Omim: 158120 Human

SwissProt: P08571 Human

Unigene: 163867 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
 
产品图片
Flow cytometry staining of normal human peripheral blood cells with CD14/FITC (bsm-30074M-FITC)(Red histogram) or Mouse IgG1 Isotype Control (FITC Conjugate)(C03-11001)(Blue histogram) . Total cells were used for analysis.